EyeQ Discs are easy to handle, conformable, and maintain strength comparable to native tissue providing ophthalmologists with the flexibility to choose the most appropriate device for each procedure and patient.
EyeQ and EyeQ Plus+ Amniotic Discs
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How Our Amniotic Membrane Discs Work
Amniotic membrane has been used for the management of a number of eye disorders including the reconstruction of the corneal epithelial surface in cases of partial limbal stem cell deficiency, corneal ulcers and perforations, severe acute inflammation and other severe ocular disorders.1 What was previously costly and difficult to obtain, is now available in a shelf-stable, cost effective solution in EyeQ.
Amniotic membrane is a unique material and its composition contains collagen types I, III, IV, V, and VII. Amniotic membrane is composed of structural extracellular matrix (ECM), that also contains specialized proteins fibronectin, laminins, proteoglycans and glycosaminoglycans. In addition, amniotic membrane contains essential healing growth factors such as epidermal growth factor (EGF), transforming growth factor beta (TGF-b), fibroblast growth factor (FGF), and platelet derived growth factor (PDGF).3 Amniotic tissues have shown little to no HLA-A, B, C antigens and β2 microglobulin.2
- Guo, Q., Hao, J., Yang, Q., Guan, L., Ouyang, S., & Wang, J. (2011). A comparison of the effectiveness between amniotic membrane homogenate and transplanted amniotic membrane in healing corneal damage in a rabbit model. Acta Ophthalmologica, 89(4). doi:10.1111/j.1755-3768.2010.02097.x
- Baradaran-Rafii A; Aghayan H; Arjmand B; and Javadi M. “Amniotic Membrane Transplantation.” Iran J Ophthalmic Res. (2)1.2007. pp 58-75.
- Kay H; Nelson D; Wang Y. “The Placenta: From Development to Disease.” Wiley-Blackwell. 2011.
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