amniotic eye dropsKeratoconjunctivitis sicca (KCS), often referred to as dry eye, is inflammation of the cornea and surrounding tissues due to inadequate production of tears. Tears are necessary to lubricate the cornea and remove debris or any infectious agents that come in contact with the eye. The tear film is a mixture of mucus, fatty liquid, and water.

Symptoms of KCS in Dogs

Most dogs with KCS will have painful, red, irritated eyes. Squinting and excessive blinking often signal a dog’s mom or dad to get their pet to a veterinary professional for treatment. Additionally, KCS often includes symptoms of thick, yellowish mucous discharge due to the lack of the watery component of the tear film. Corneal ulceration may also be present.

Patients with chronic cases of KCS often present with a history of conjunctivitis, eye injuries, and ulcers. Corneal scarring, hyperpigmentation, usually occurs with cases of KCS and looks like a dark film covering the dog’s eye.

Is A Dog More Likely to Contract KCS Because of Their Breed?

KCS most commonly affects middle-aged to older dogs. It’s more likely to be seen in the following breeds:

  • American Cocker Spaniel
  • Bloodhound
  • Boston Terrier
  • Cavalier King Charles Spaniel
  • English Bulldog
  • English Springer Spaniel
  • Lhasa Apso
  • Miniature Schnauzer
  • Pekingese
  • Pug
  • Samoyed
  • Shih Tzu
  • Yorkshire Terrier

Both eyes are typically affected in dogs with KCS, but one eye may appear worse.

Treatment of KCS in Dogs

There are two main objectives when treating KCS in dogs:

  • Stimulate tear production
  • Replace the tear film and protect the cornea

Tear film replacement and tear production stimulants are often used in combination first. However, Veterinarians manage most KCS cases in dogs with a combination of tear stimulants, tear substitutes, antibiotics, and anti-inflammatories. Surgery for KCS is reserved for dogs who do not respond to medication and are experiencing persistent pain. Secondary bacterial conjunctivitis is common in dogs with KCS due to debris accumulation and a lack of natural antimicrobial tear properties. Additionally, patients often experience much discomfort and pain with KCS and the ulceration that often accompanies it. Anti-inflammatory and antibiotic combinations are helpful for improving comfort and diminishing corneal opacities.

Vetrix created a solution for veterinarians, EyeQ Amniotic Eye Drops, to deliver natural antimicrobial and anti-inflammatory components alongside traditional therapies when treating KCS. EyeQ is an easy-to-use, non-surgical option for treating corneal defects and ulcers and keeping a dog as comfortable as possible throughout treatment. What’s more, EyeQ allows easy administration for veterinarians and dog owners alike. The medicine comes in a convenient dropper bottle and is available to veterinary professionals in 6-pack, 12-pack, and 24-pack options.

Provide The Best Care for Your Dog

Getting attached to dogs you see regularly (even if they aren’t your dog) is easy. We can all agree that when it comes to treating dogs with KCS, all we want is for the animal to get better. If you’re a Vet who intends to provide the best care for the KCS and ulcer cases you see in dogs, try out a 6-pack of EyeQ for yourself. If you’re not completely satisfied, Vetrix will work with you to return your purchase.

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Eye Drops for Pets

The cornea, which is transparent in normal conditions, covers the front part of the eye and allows light to pass into the eye. The eyelids cover the cornea to protect it from trauma and help spread tears (essential to corneal health). Most corneal ulcers in pets result from trauma, such as scratches, dry eye, eyelid anomalies, or abrasions due to foreign objects in the eye.

Corneal Ulcer Symptoms

A corneal ulcer is an open wound within the cornea. Ulcers are painful for pets; most heal within a week if appropriately treated. However, if a corneal ulcer becomes infected, it can quickly turn into a deep wound. The most common symptoms of corneal ulcers to watch for in pets include the following:

  • Squinting
  • Redness
  • Ocular discharge
  • Excessive Blinking
  • Excessive tears
  • Swelling
  • The eye appears cloudy

If the ulcer results from a tear deficiency, you may see a thick discharge resembling mucous that ranges from transparent to white, green, or yellow. If you are a cat parent, a dog parent, or a veterinarian who wants to provide helpful materials to your patients of specific pets, please read the following information:

Corneal Ulcer Diagnosis

Any of the signs mentioned above should prompt pet parents to make an appointment with their veterinarian. The vet will use several diagnostic methods at the appointment to accurately diagnose the ulcer. Once the affected eye (or eyes) are examined, your vet will discuss the best possible treatment plan.

Corneal Ulcer Treatment

How a pet’s corneal ulcer is treated is determined by the type of animal in need of treatment and the type of ulcer they are being treated for. Treating corneal ulcers properly from the start is crucial to ensuring a pet’s comfort and healing without further complications or damage to its vision. Mild corneal ulcers will usually heal on their own in 3-7 days, depending on the size of the ulcer. While healing, vets may recommend a treatment plan to prevent further damage or cornea infections. 

Here are common treatments used to treat corneal ulcers in pets:

  • Antibiotic eye drops or ointments to prevent infections
  • Pain medication to keep your pet comfortable
  • An E-collar to prevent your pet from rubbing and allow the cornea to heal properly
  • Regenerative eye drops 

Regenerative eye drops, like Vetrix EyeQ Eye Drops, are a simple way to provide regenerative care for a pet’s eye. Regenerative medicine works with the body’s natural abilities to heal itself. EyeQ Eye Drops deliver natural anti-microbial and anti-inflammatory components to aid in healing corneal ulcers in pets. 

As part of the healing process, a follow-up care plan must be issued and adhered to by the patient. Pets should continue treatment with all prescribed medications until a veterinarian says the ulcer has fully healed.

The canine eye is much more resilient than a lot of people would expect to trauma, but this is still one of the most at-risk parts of the dog’s body. For this reason, corneal ulcers are quite the common reason for a visit to the vet.

While common, corneal ulcers should never be treated as a general situation that does not require veterinary or medical intervention. If the ulcer does not heal properly, the dog’s visual capabilities can be affected. Below, we will take a look at what a corneal ulcer actually is, what causes it, and how the condition may be treated.

What Is the Cornea of a Dog’s Eye?

The cornea, simply put, is the thin membrane that covers the forward-facing part of the eyeball. The membrane is completely transparent, almost like a window that protects the inner structures of the eye. The full cornea is about half as thick as a dime.

The dog’s cornea, much like a human’s cornea, is made up of different layers: the outer layer of epithelium, the interior layer of stroma, and the Descemet membrane at the deepest point. All three layers of the cornea are clear, making it impossible to discern between them with the naked eye. In order to examine the cornea, veterinarians use special pigmented eye drops with a green dye that highlights cells of specific layers of the cornea.

What Is a Corneal Ulcer?

Corneal ulcers are abrasions (sores) of the outer surface of the eye that protects the pupil, iris, and aqueous humor. Medically, corneal ulcers may be referred to as ulcerative keratitis. The abrasion causes inflammation, swelling, and can be slow to heal depending on the depth of the trauma. The ulcers in a dog’s cornea can range in severity from superficial to deep, depending on which layers of the cornea are injured.

Types of Corneal Ulcers in Dogs

Corneal ulceration can be superficial or a deeper problem that reaches into the corneal stroma, and sometimes all the way into the Descemet’s membrane. Here is a more thorough explanation of some of the types of corneal ulcers that dogs can have.

Superficial Ulcers

Superficial ulcers are sometimes referred to as superficial corneal abrasion or corneal erosion, and they affect only the epithelium layer. Superficial corneal ulcers are the easiest to treat and often do not require medical intervention to heal properly. However, topical antibiotics for the corneal surface may be vet-recommended until the ulcer heals.

Stromal Ulcers

Stromal ulcers affect the corneal stroma and can be much more threatening to the eye and the dog’s comfort level. The stroma is actually laced with nerves, which means damage to this layer of the cornea can bring about significant pain for the dog. Stromal ulcers take longer to heal than superficial corneal abrasions, and medical intervention with antibiotic eye drops is often a must to prevent infection.

Descemetoceles and Perforations

Ulcers that reach into the Descemet’s membrane are referred to as descemetoceles. When an ulcer actually goes completely through the Descemet’s membrane, this is referred to as corneal perforation. 

Both descemetoceles and perforations may need to be surgically treated in an effort to preserve the eye, even though an aggressive effort to medicinally manage the problem may suffice for some dogs. Serious complications, such as vision loss and a need to remove the eye are more common with these types of ulcers.

Indolent Ulcers

Indolent ulcers, which are also referred to as spontaneous chronic corneal epithelial defects (SCCEDs), are non-healing ulcers that are usually caused by trauma. These ulcers are more common in older dogs, most often diagnosed around eight or nine years of age. 

Even though by definition an indolent ulcer is superficial, sometimes, an indolent ulcer will actually get infected and affect the stroma. With this particular type of ulcer, improper healing can be to blame; the surface layer epithelium can actually be loosely attached to the underlying stroma.

How a Corneal Ulcer Occurs

Corneal ulcers in dogs can occur for several reasons, even though the biggest causative factor is usually some type of trauma to the dog’s eye. A dog’s eye may sustain trauma by a direct, blunt hit to the eye, foreign material under its eyelid, and even just by scratching with its own paws and nails.

A few other causes of corneal ulcers in dogs include:

  • Illness or disease
  • Lacking tear production
  • Eyelid rolling or inability to close the eyelids
  • Chemical burns
  • Eye infections
  • Facial nerve paralysis that affects eyelid movement

Some dog breeds can actually be more prone to corneal ulcers than others due to the shape of their eyes and the surrounding lids. For example, breeds with shorter noses and prominent eyes that seem to protrude a bit from the face like Pugs and Boxers, are more likely to sustain corneal ulcers.

Signs and Symptoms of a Corneal Ulcer in Dogs

One of the good things about corneal ulcers is the fact that most dog owners will readily recognize that something is wrong with their dog’s eye so they can seek veterinary care. A few signs and symptoms during the initial stages of a corneal ulcer include:

  • Ocular discharge
  • Squinting
  • Sensitivity to light
  • Watery eyes
  • Pawing at the eyes
  • Holding the eye closed
  • Redness or inflammation of the eye
  • Film development over the eye

Usually, dogs will show signs that their eye is injured or causing problems a lot during the first few days after the trauma occurs.

How Does a Corneal Ulcer Affect Your Dog?

Dogs with corneal ulcers may be affected in different ways depending on the severity of the condition. Sometimes, a surface-layer abrasion won’t seem to make much of a difference to the dog or the dog’s ability to see and get around. However, deeper abrasions can be painful and have a higher likelihood of affecting the dog’s vision.

Even though trauma to the eye is assumed to always be painful, this may not be the case with every corneal ulcer. While the issue can be recognizable upon visual inspection, injury to the corneal surface may only cause some slight discomfort, so a dog may not be in pain or show any major signs of distress.

Unfortunately, however, some corneal ulcers can be painful. As noted above, abrasions that go deeper than the corneal epithelium can be extremely uncomfortable for the dog. The vet may offer pain-relieving eye drops because of this.

Can a Dog Go Blind from a Corneal Ulcer?

Dogs can lose their vision to a corneal ulcer, especially if the condition is left untreated or if the proper steps are not taken to promote healing. For example, if the dog has a stromal ulcer, which carries a high risk of infection, and the condition is left untreated with antibiotic drops and gets infected, the chance the dog will lose its sight is high.

Another important factor, a scar on the surface of the cornea that develops during the healing process can lead to corneal opacity. This makes part of the eye appear as if it has clouded over, but it also makes it impossible for light to properly get to the optic nerve. Therefore, the dog’s visual capacity can be affected. In some cases, the right treatments during the healing process can help deter heavy scar formation.

Corneal opacity caused by scarring after an ulcer should not be confused with corneal dystrophy. Corneal dystrophy also causes opacity, but this is a result of some kind of genetic malfunction that interferes with how the dog’s body metabolizes fat. Fatty deposits can collect in the eye and cause similar cloudiness that impedes visual capacity over time.

Typical Corneal Ulcer Dog Treatment

Treatment for corneal ulcers in canines depends on the type of ulcer diagnosed. General corneal abrasions may need no treatment at all; the mild abrasions may heal on their own within a few days. Nevertheless, medication may be used as a preventive measure to prevent an ophthalmic infection. Some of the more typical methods of treating corneal ulcers include:

  • Antibiotic eye drops
  • Topical antibiotic ointments
  • Eye drops with a pain reliever

When surgery is necessary to treat a corneal ulcer, a few different procedures may be used. For example, corneal diamond burr debridement surgery is a procedure performed with a diamond burr that gently removes the damaged corneal tissue to promote proper healing.

Regenerative Care for Canine Corneal Ulcers

Treating corneal defects is not an easy feat; so many things can inhibit the healing process and cause problems for the dog’s vision for the long term. Ideally, treatment would help the corneal tissue regenerate and repair itself with little disruption to the dog’s vision. Therefore, a more modern inclusion tactic in the treatment of corneal ulcers is using regenerative solutions.EyeQ Eye Drops from Vetrix is an easy way to offer regenerative care to the dog’s eye. These amniotic eye drops utilize innate growth factors and other components that modulate inflammation, offer just enough lubrication for protection, and promote healing by encouraging cellular growth. To find out more about EyeQ Eye Drops and corneal ulcers in canines, be sure to download the Corneal Ulcer Quick Guide.

If you often treat patients in your practice with corneal ulcers and defects, then Vetrix EyeQ Amniotic Eye Drops may be a solution for you to offer them. These eye drops promote healing, modulate inflammation, and provide long-lasting lubrication. Keep reading to see how they helped a 9-year-old terrier mix canine from losing his eye.

The Patient & The Problem

After trying every medication recommended by their primary veterinarian, pet owners were referred to Board Certified Veterinary Ophthalmologist, Dr. Kirsten Steele. Their dog’s eye condition was continuing to get worse. If his condition didn’t improve, his eye would need to be removed.

Before trying Vetrix EyeQ Amniotic Eye Drops, Dr. Steele used various treatment methods that yielded no improvement to the dog’s corneas. She then started treatment using Vetrix EyeQ in the eye with ulcers, intending to treat both the ulcer and the inflammation. Within two weeks, the owners reported the corneal ulcers completely healed. Their dog would no longer need to have his eye removed.

Vetrix EyeQ Amniotic Eye Drops—The Solution

After reporting an increase in comfort while on the Amniotic Eye Drops, Dr. Steele recommended use in both eyes to treat the dry eye. She started the dog out on a TID medication schedule and then decreased to BID. Dr. Steele reported that while the eyes were not producing tears and were still a bit inflamed, there was a reduction in blepharospasm. She decided to keep the pet on traditional tear stimulant medications to help with conjunctival goblet cell health.

Dr. Steele achieved complete healing of the ulcers using Vetrix EyeQ Amniotic Eye Drops and restarted a topical steroid and antibiotic combination to treat the remaining inflammation. She reported that the Eye Drops were an effective solution for a patient that wasn’t responding to traditional treatments for dry eye.

The Part We Love

The owners are overjoyed and relieved that their dog doesn’t have to have his eye removed. They’re also grateful that his ulcers and dry eye are under control, that he is no longer in pain, and that his eyesight is improving. Now he can be the energetic and playful pup he once was.
If you think our EyeQ Amniotic Eye Drops may be helpful for patients in your practice, or you’d like more information, contact us here. We’d love to answer any questions you may have! And if you’d like to read more interesting information on topics like this, visit our blog.