Revolutionizing Veterinary Wound Care with Healion: A Case Study in Regenerative Medicine

In the ever-evolving field of veterinary medicine, innovative products like Healion Amniotic Wound Matrix are setting new standards for wound healing. By utilizing the powerful properties of amnion, Healion provides veterinarians with a reliable and effective tool for treating complex wounds, enhancing the natural healing process. This blog post will explore the remarkable healing journey of a turtle, showcasing the benefits of Healion in veterinary wound care.

The Role of Amnion in Regenerative Medicine

Amnion, the innermost layer of the placenta, is packed with growth factors, anti-inflammatory properties, and essential proteins that are crucial in wound healing. The Healion Amniotic Wound Matrix, derived from this unique tissue, is delivered in a powdered form, making it easy to apply. This product promotes rapid tissue regeneration, reduces inflammation, and provides a bioscaffold for new cells to grow, making it an invaluable solution in regenerative medicine.

Case Study: A Turtle’s Fast-Track to Recovery

Dr. Garry Innocent, a veterinarian at All Species 24hr Clinic in Alpharetta, GA, encountered an exotic patient with a severe head injury. The turtle had been scalped, leaving no tissue to facilitate traditional wound closure. Faced with this daunting challenge, Dr. Innocent turned to Healion Amniotic Wound Matrix.

Within 24-36 hours of applying Healion, the results were nothing short of extraordinary. The wound began healing rapidly, showing organized, healthy tissue growth. Dr. Innocent expressed his satisfaction, noting that Healion was simple to apply and did not lead to further complications, unlike traditional wound treatments which sometimes cause additional trauma.

For a case where minimal tissue was available and the delicate nature of the patient complicated suturing, Healion’s trauma-free application was the perfect solution. The turtle’s speedy recovery demonstrates the effectiveness of this regenerative wound care tool across different species.

Why Healion Is Essential for Veterinarians

Healion’s amnion-based matrix provides a safe, versatile, and easy-to-use solution for a wide range of wound types, including surgical wounds, trauma injuries, and ulcers. Its unique properties not only accelerate healing but also minimize scarring, making it a preferred choice in complex cases where traditional methods fall short.

The ability to promote natural tissue regeneration without causing additional trauma makes Healion indispensable for treating patients where suturing isn’t viable or safe. Additionally, its application is simple, reducing the stress for both veterinarian and patient, whether treating small, exotic animals or common household pets.

Conclusion

Healion Amniotic Wound Matrix is revolutionizing the way veterinarians approach wound healing. By leveraging the regenerative properties of amnion, it offers an effective solution for complex wounds that are difficult to close or heal. In the case of Dr. Innocent’s turtle, Healion proved its ability to facilitate fast, trauma-free healing in a delicate patient, underscoring its versatility and power as a regenerative medicine product. For veterinarians seeking reliable and advanced wound care options, Healion is a must-have in the medical toolkit.

Small dog on a vet’s tableBite wounds are one of the most common reasons dogs see their veterinarians. If a dog is bitten or gets into a fight with another dog, this is what needs to happen first:

  1. As the dog’s owner, stay calm. Panic will only make the situation worse.
  2. Don’t get between your dog and the other dog(s) to break up the fight. You could also get bit in the process.
  3. Focus on getting your dog away from the other dog. A loud clap or another distracting sound may help get your dog’s attention so you can call or signal him to you.
  4. Don’t scream at the other dog, as this could make the situation feel even more threatening to the dogs.
  5. Ask the other dog owner (if present) if their dog is up to date on their vaccines. If the pet owner isn’t present or the other dog involved is a stray, try to get pictures at the very least.
  6. Once your dog is safely away from the dog who bit him, contact your vet immediately or head to your nearest emergency animal hospital.

Why Do Dogs Bite?

Biting is often part of play for puppies. In adult dogs, multiple motives or causes for biting can stem from competitive issues or reactions to perceived threats. Additionally, several factors influence the severity of a dog bite and the health risk it can pose to a pet. This is why seeing your veterinarian as quickly as possible after your dog has experienced a bite is a good idea.

Treating Bite Wounds in Dogs

Dog bites can cause significant injury to the skin and soft tissues. A dog’s teeth and jaws are powerful; a bite wound can result in torn muscles and skin. Not all bite wounds are big, though. Just because a bite wound is small doesn’t mean it isn’t a cause for concern. Minor bites can heal themselves quickly but, in doing so, can trap bacteria in the wound that can result in an abscess.

Infections are the primary concern for any dog bite, but other serious issues can develop if not treated properly. Typically, a vet will examine and thoroughly clean the bite wound and then provide a broad-spectrum antibiotic to help fight infection and prevent further complications with the wound site. Or, the vet can use Vetrix’s Healion Amniotic Wound Matrix as part of their patient’s bite wound treatment plan. 

Healion is a decellularized amniotic membrane supplied in fine, dry, sterilized white powder form for veterinary use. Healion amniotic wound matrix leverages the natural healing properties of the amnion to modulate inflammation and create an environment conducive to rapid cell migration.

You apply it to the wound site and appropriately bandage it to create a sterile healing environment. The bite should be re-examined every 4-5 days, and a single application is usually sufficient.

How To Help A Dog Heal After A Bite

As a vet, your priority is preventing your patient’s bite wound from getting infected. Start treating bite wounds with a fast and effective treatment option that makes patients and clients happy. Add Healion to your medical toolkit today. Order now.

BioSIS wound dressing photolarge copyAny veterinarian worth their salt knows that providing superior wound care treatment starts with assessing the overall stability of the animal. Once the patient is stable, the next step is administering first aid for the wound as soon as safely possible. Your treatment should follow the fundamentals of debridement, infection or inflammation control, and moisture balance. Success depends on taking the correct approach and deciding whether to manage the wound as open or closed.

Before considering surgery, veterinarians looking for a more effective wound treatment should explore Healion Amniotic Matrix. The solution is an easy-to-use, sterilized powder that promotes the healing of wound sites.

Provide Superior Wound Care with Healion Wound Matrix

When choosing wound care solutions for your patients, protecting the wound sight from further contamination and trauma is often a top concern. This is where Healion Wound Matrix can help, especially in situations where a wound cannot or should not be closed. Healion is a decellularized amniotic membrane supplied in fine, dry, sterilized white powder form for veterinary use. It leverages the natural healing properties of amnion to modulate inflammation and create an environment conducive to rapid cell migration. All you must do is puff the solution onto the wound bed and cover it with a non-adherent bandage.

Once administered, and as we touched on at the beginning of this post, it’s advised you consider the following four things while caring for your wound patient:

  1. Giving the wound proper support
  2. Maintaining proper moisture levels
  3. Mitigating infection risk
  4. The phases of wound healing

If these four factors aren’t considered when bandaging and monitoring your patient, you might not see the healing you expect. (Remember pain management throughout the phases of recovery, too.)

Healion Wound Matrix serves as a wound care solution where open wound management or delayed wound closure is the best course of action for the patient. Healion is uniquely designed to enable veterinarians to provide superior wound care treatment and is indicated for the management of wounds, including:

 

  • Partial wounds
  • Full-thickness wounds
  • Surgical wounds
  • Trauma wounds
  • Draining wounds

Do You Want to Provide Superior Wound Care Treatment?

It’s time to join top veterinarians using the best regenerative wound care technology and provide your patients with faster and more effective treatment options. Healion Wound Matrix provides an ideal healing environment and flexibility in treating both acute and chronic wounds, and it’s affordable.

Healion is cost-effective and packaged to fit procedural needs. Learn about Healion Wound Matrix pricing (available in 6-pack, 12-pack, and 24-pack options).

The canine eye is much more resilient than a lot of people would expect to trauma, but this is still one of the most at-risk parts of the dog’s body. For this reason, corneal ulcers are quite the common reason for a visit to the vet.

While common, corneal ulcers should never be treated as a general situation that does not require veterinary or medical intervention. If the ulcer does not heal properly, the dog’s visual capabilities can be affected. Below, we will take a look at what a corneal ulcer actually is, what causes it, and how the condition may be treated.

What Is the Cornea of a Dog’s Eye?

The cornea, simply put, is the thin membrane that covers the forward-facing part of the eyeball. The membrane is completely transparent, almost like a window that protects the inner structures of the eye. The full cornea is about half as thick as a dime.

The dog’s cornea, much like a human’s cornea, is made up of different layers: the outer layer of epithelium, the interior layer of stroma, and the Descemet membrane at the deepest point. All three layers of the cornea are clear, making it impossible to discern between them with the naked eye. In order to examine the cornea, veterinarians use special pigmented eye drops with a green dye that highlights cells of specific layers of the cornea.

What Is a Corneal Ulcer?

Corneal ulcers are abrasions (sores) of the outer surface of the eye that protects the pupil, iris, and aqueous humor. Medically, corneal ulcers may be referred to as ulcerative keratitis. The abrasion causes inflammation, swelling, and can be slow to heal depending on the depth of the trauma. The ulcers in a dog’s cornea can range in severity from superficial to deep, depending on which layers of the cornea are injured.

Types of Corneal Ulcers in Dogs

Corneal ulceration can be superficial or a deeper problem that reaches into the corneal stroma, and sometimes all the way into the Descemet’s membrane. Here is a more thorough explanation of some of the types of corneal ulcers that dogs can have.

Superficial Ulcers

Superficial ulcers are sometimes referred to as superficial corneal abrasion or corneal erosion, and they affect only the epithelium layer. Superficial corneal ulcers are the easiest to treat and often do not require medical intervention to heal properly. However, topical antibiotics for the corneal surface may be vet-recommended until the ulcer heals.

Stromal Ulcers

Stromal ulcers affect the corneal stroma and can be much more threatening to the eye and the dog’s comfort level. The stroma is actually laced with nerves, which means damage to this layer of the cornea can bring about significant pain for the dog. Stromal ulcers take longer to heal than superficial corneal abrasions, and medical intervention with antibiotic eye drops is often a must to prevent infection.

Descemetoceles and Perforations

Ulcers that reach into the Descemet’s membrane are referred to as descemetoceles. When an ulcer actually goes completely through the Descemet’s membrane, this is referred to as corneal perforation. 

Both descemetoceles and perforations may need to be surgically treated in an effort to preserve the eye, even though an aggressive effort to medicinally manage the problem may suffice for some dogs. Serious complications, such as vision loss and a need to remove the eye are more common with these types of ulcers.

Indolent Ulcers

Indolent ulcers, which are also referred to as spontaneous chronic corneal epithelial defects (SCCEDs), are non-healing ulcers that are usually caused by trauma. These ulcers are more common in older dogs, most often diagnosed around eight or nine years of age. 

Even though by definition an indolent ulcer is superficial, sometimes, an indolent ulcer will actually get infected and affect the stroma. With this particular type of ulcer, improper healing can be to blame; the surface layer epithelium can actually be loosely attached to the underlying stroma.

How a Corneal Ulcer Occurs

Corneal ulcers in dogs can occur for several reasons, even though the biggest causative factor is usually some type of trauma to the dog’s eye. A dog’s eye may sustain trauma by a direct, blunt hit to the eye, foreign material under its eyelid, and even just by scratching with its own paws and nails.

A few other causes of corneal ulcers in dogs include:

  • Illness or disease
  • Lacking tear production
  • Eyelid rolling or inability to close the eyelids
  • Chemical burns
  • Eye infections
  • Facial nerve paralysis that affects eyelid movement

Some dog breeds can actually be more prone to corneal ulcers than others due to the shape of their eyes and the surrounding lids. For example, breeds with shorter noses and prominent eyes that seem to protrude a bit from the face like Pugs and Boxers, are more likely to sustain corneal ulcers.

Signs and Symptoms of a Corneal Ulcer in Dogs

One of the good things about corneal ulcers is the fact that most dog owners will readily recognize that something is wrong with their dog’s eye so they can seek veterinary care. A few signs and symptoms during the initial stages of a corneal ulcer include:

  • Ocular discharge
  • Squinting
  • Sensitivity to light
  • Watery eyes
  • Pawing at the eyes
  • Holding the eye closed
  • Redness or inflammation of the eye
  • Film development over the eye

Usually, dogs will show signs that their eye is injured or causing problems a lot during the first few days after the trauma occurs.

How Does a Corneal Ulcer Affect Your Dog?

Dogs with corneal ulcers may be affected in different ways depending on the severity of the condition. Sometimes, a surface-layer abrasion won’t seem to make much of a difference to the dog or the dog’s ability to see and get around. However, deeper abrasions can be painful and have a higher likelihood of affecting the dog’s vision.

Even though trauma to the eye is assumed to always be painful, this may not be the case with every corneal ulcer. While the issue can be recognizable upon visual inspection, injury to the corneal surface may only cause some slight discomfort, so a dog may not be in pain or show any major signs of distress.

Unfortunately, however, some corneal ulcers can be painful. As noted above, abrasions that go deeper than the corneal epithelium can be extremely uncomfortable for the dog. The vet may offer pain-relieving eye drops because of this.

Can a Dog Go Blind from a Corneal Ulcer?

Dogs can lose their vision to a corneal ulcer, especially if the condition is left untreated or if the proper steps are not taken to promote healing. For example, if the dog has a stromal ulcer, which carries a high risk of infection, and the condition is left untreated with antibiotic drops and gets infected, the chance the dog will lose its sight is high.

Another important factor, a scar on the surface of the cornea that develops during the healing process can lead to corneal opacity. This makes part of the eye appear as if it has clouded over, but it also makes it impossible for light to properly get to the optic nerve. Therefore, the dog’s visual capacity can be affected. In some cases, the right treatments during the healing process can help deter heavy scar formation.

Corneal opacity caused by scarring after an ulcer should not be confused with corneal dystrophy. Corneal dystrophy also causes opacity, but this is a result of some kind of genetic malfunction that interferes with how the dog’s body metabolizes fat. Fatty deposits can collect in the eye and cause similar cloudiness that impedes visual capacity over time.

Typical Corneal Ulcer Dog Treatment

Treatment for corneal ulcers in canines depends on the type of ulcer diagnosed. General corneal abrasions may need no treatment at all; the mild abrasions may heal on their own within a few days. Nevertheless, medication may be used as a preventive measure to prevent an ophthalmic infection. Some of the more typical methods of treating corneal ulcers include:

  • Antibiotic eye drops
  • Topical antibiotic ointments
  • Eye drops with a pain reliever

When surgery is necessary to treat a corneal ulcer, a few different procedures may be used. For example, corneal diamond burr debridement surgery is a procedure performed with a diamond burr that gently removes the damaged corneal tissue to promote proper healing.

Regenerative Care for Canine Corneal Ulcers

Treating corneal defects is not an easy feat; so many things can inhibit the healing process and cause problems for the dog’s vision for the long term. Ideally, treatment would help the corneal tissue regenerate and repair itself with little disruption to the dog’s vision. Therefore, a more modern inclusion tactic in the treatment of corneal ulcers is using regenerative solutions.EyeQ Eye Drops from Vetrix is an easy way to offer regenerative care to the dog’s eye. These amniotic eye drops utilize innate growth factors and other components that modulate inflammation, offer just enough lubrication for protection, and promote healing by encouraging cellular growth. To find out more about EyeQ Eye Drops and corneal ulcers in canines, be sure to download the Corneal Ulcer Quick Guide.

Treating wounds is part of everyday life in a veterinary practice. Vets encounter different types of injury daily from accidental wounds to surgical or recurring wounds, all requiring different types of wound management according to the patient. 

Supporting wounds and offering the best in regenerative technology can ensure that the healing time is cut down and the patient is on the right track. The Vetrix Healion amniotic wound matrix is paving the way for regenerative medicine. 

What Is the Healion Amniotic Wound Matrix? 

The wound matrix developed by Vetrix is a regenerative decellularized amniotic membrane; the material consists of collagen and an extracellular matrix. The matrix is rich in proteins, laminins, and proteoglycans. 

The matrix stimulates healing and growth of the dermis while ensuring that wounds heal faster and better with fewer complications. Naturally occurring growth factors within the matrix stimulate the regeneration of the epidermis and offer protection at the wound site. 

The Benefits Of Vetrix Wound Matrix

There are many benefits to using an amniotic wound matrix. Reducing your patient’s healing time can significantly reduce the risk of infection and complications that could arise from prolonged wound management. 

  • Setting the right environment – The Vetrix Healion creates the perfect healing environment. The amniotic matrix sets the healing environment right, allowing tissues to repair effectively and efficiently. 
  • Sterile – The sterile applicator ensures that you are not inserting anything into the wound that could compromise healing. 
  • Ease of use – Healion is packaged in a unique dispenser; the ergonomic design is created for ease of use and allows hard-to-treat areas to be accessed with ease.
  • Cost-effective – Faster healing wounds cost less. The Vetrix matrix is a cost-effective solution for your practice’s wound management needs. By reducing the need for patients to return, they save on pricey wound maintenance trips to your practice. 
  • Single application – The wound matrix is efficient enough to be used in a single application in most cases. More complex wounds might require an additional application of the Vetrix Healion; however, a single application is needed for most injuries. 
  • Open wound care – The matrix modulates inflammation and stimulates a healing environment. 

Investing in wound care can resolve some of the most complicated wounds, allowing animals to return to their regular lives sooner, reducing stress and frustration for veterinary practices, owners, and the animals themselves. 

If you have any concerns or want any additional information – get in touch with Vetrix; we are happy to answer any questions and walk you through the Healion Wound Matrix.

August 2018

This months’ case comes to us from Dr. Mike Herrington DVM. He leverages Healion, Vetrix’s amnion wound particulate to close a mass removal.

Dr. Herrington practices at Englewood Animal Health Center in Englewood, FL. Read below to learn why he used Healion and his results utilizing this technology.

Case background: “Gracie is a 6yr old F/S Boxer mix who presented for removal of about a 1.5cm dermal mass on the dorsal mid shaft R forelimb. The mass removal was the easy part, but closure was difficult. The mass was directly over the cephalic vein, so I did not want to leave it open. I had to undermine completely around the circumference of the leg and make about 2 dozen mesh incisions, as well subQ anchors just to get the skin apposed. Even so it was tight, so I splinted it and applied a modified Robert Jones bandage. I performed daily wet-dry bandage changes, using Entederm (nystatin-neomycin-triamcinolone) ointment, mainly for the anti-inflammatory properties. The skin just didn’t stretch as much as I was hoping, and the cephalic vein was being compressed, so her foot became edematous and the skin around the incision is showing some focalized necrosis. On April 7th I made 2 releasing incisions under bupivicaine, taking great care to leave the cephalic vein covered. I was able to massage a good amount of the edema out. I replaced the splint & bandage, this time switching to silvadene cream. She is also on carprofen and cephalexin orally BID.” – Dr. Herrington

Initial Healion Application

Healion was initially applied on 4/11/18, 8 days after surgery, to the releasing incision sites. Gracie got her bandage off 3 days later and licked the Healion off the wound.

Reapplying Healion

Healion was reapplied per suggestion from Vetrix on 4/16/18. No further complications occurred.

4 Days Post Second Application

Healing proceeded well, a healthy granulation bed formed by 4/19/18. The splint was removed from the bandage on 4/20/18 (4 days post Healion application), with Gracie able to fully bear weight on the affected leg.

5/4/2018 (18 Days post Healion application)

Bandaging was maintained to protect the healing wound.

5/14/2018 (28 days post Healion application)

Epithelialization proceeded well, and was complete on 5/14/18. Carprofen and cephalexin therapy was maintained until 5/14/18.

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